'Splice': Your Results May Vary (And Be Scary) (2024)

Mom? Dren may be a modern-day Frankenstein's monster, but Delphine Chaneac plays her with a mythical beauty and ballerina's grace. Sarah Polley stars as Elsa, one of the creature's two creators. Warner Bros. hide caption

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Warner Bros.

Creating new life is a messy business -- so said Mary Shelley, writing in the early 19th century in Frankenstein, or The Modern Prometheus. So you'd think, given all the gene-mapping and cloning going on nowadays, that horror movies would be lousy with Frankenstein scenarios -- cautionary tales in which technology outpaces our understanding of how to use it. But mostly we have splatter flicks, torture p*rn and lame remakes. In that context, Vincenzo Natali's Splice calls to us like a luminous laboratory beaker. What a strange and wonderful brew!

It's set in Toronto and owes a lot to David Cronenberg, especially his films The Brood and The Fly. Throw in Splice and you can start to define an Ontario subgenre: faceless, sterile modern settings, wintry and blue-lit, in which monsters are grown or hatched. And those monsters have a metaphorical component; they're as much a product of wayward emotions as of liberated biochemistry.

In Splice, Canada's own Sarah Polley and long-faced Adrien Brody play Clive and Elsa, celebrated nerdy scientists splicing genes for a pharmaceutical company -- called, in fact, NERD, for Nucleic Exchange Research and Development. When we meet them, they're delivering a new life form, literally, from some kind of pulsing ovum in an incubator -- a giant, wormy, wriggling mass of tissue from which they're going to mine all kinds of patent-worthy medical processes.

But then company bigwigs put the kibosh on future research: Use what's there and generate capital, they command. That's when Clive and Elsa think: Why not mix in some human DNA and see what grows? Just to, you know, prove they can. After a lot of tinkering, the implant takes. The fetus -- a kitchen sink's worth of species -- comes quickly to term. And then we hear the words immortalized first in 1931 by Frankenstein's Colin Clive: "It's alive."

Clive is about to gas the lab and kill the infant creature, but to stop him, Elsa whips off her oxygen helmet. That's the first sign in Splice that the two will approach this "child" from different angles. Clive, very nervous, wants to kill it. Elsa develops less scientific feelings.

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It's Alive: Polley and Adrien Brody star as nerdy scientists who inadvertently create the humanoid Dren as part of a genetic research project for a pharmaceutical giant. Warner Bros. hide caption

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Warner Bros.

It's Alive: Polley and Adrien Brody star as nerdy scientists who inadvertently create the humanoid Dren as part of a genetic research project for a pharmaceutical giant.

Warner Bros.

What's endlessly fascinating in Splice is trying to get a handle on what the creature is. Elsa calls it "Dren," nerd spelled backwards, and it's seemingly female.

First it's a pile of flesh with eyes on either side of its head. Then, quickly, since its growth is accelerated, it begins to look humanoid, albeit with other components, from amphibious to avian -- plus a long tail with a lethal spike. It has no language you'd recognize -- clicks and rattles and chirps.

When Dren makes too much of a racket, Elsa and Clive sneak her down -- she's wearing a cute little dress -- to their facility's dank basem*nt.

"I don't know about this," says Clive.

"You got a better idea?" asks Elsa.

"I'm starting to feel like a criminal," he says.

"Scientists push boundaries," his wife says. "At least, important ones do."

You know no good will come from this, right? But the way in which it all goes bad has a distinctly human dimension. It turns out that Elsa, so militantly maternal, had an abusive mom -- and as Dren grows over a couple of months and becomes more assertive, like a mischievous child and then a rebellious teenager, something dark and scary in Elsa takes hold. And Clive, who wanted to destroy Dren, begins to soften. Soon this high-tech Frankenstein acquires a vein of freaky, low-tech Gothic psychodrama.

Brody and Polley are thoroughly convincing when their characters are smart, and only slightly less so when they turn crazy-dumb. But then Dren could drive anyone mad: The Paris-born actress Delphine Chaneac plays the maturing monster with help from creature effects designer Howard Berger, and she has her own mythical beauty. Her head tilts, birdlike, as her wide almond eyes take in her new world. She totters on colt legs above bird feet, but with a ballerina's poise.

I'm sad to say the climax of Splice feels too rushed. But if gene-splicing can give us monsters as poetically strange as Dren, it bodes well for our horror movies -- if not necessarily for our species. (Recommended)